Cyklokapron

Generic Name: tranexamic acid (Intravenous route)

tran-ex-AM-ik AS-id

Commonly used brand name(s)

In the U.S.

• Cyklokapron

Available Dosage Forms:

• Solution

Therapeutic Class: Hemostatic

Uses For Cyklokapron

Tranexamic acid injection is used to control or prevent excessive or heavy bleeding during dental procedures in patients with hemophilia. This medicine is for short-term use only, usually 2 to 8 days.

Tranexamic acid injection is an antifibrinolytic agent. It works by blocking the breakdown of blood clots. It may also be used for other conditions as determined by your doctor.

This medicine is available only with your doctor's prescription.

Before Using Cyklokapron

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of tranexamic acid injection in children.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tranexamic acid injection in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving tranexamic acid injection.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	B	Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Anti-Inhibitor Coagulant Complex


• Chlorpromazine


• Desogestrel


• Dienogest


• Drospirenone


• Estradiol Cypionate


• Estradiol Valerate


• Ethinyl Estradiol


• Ethynodiol Diacetate


• Etonogestrel


• Levonorgestrel


• Medroxyprogesterone Acetate


• Mestranol


• Norelgestromin


• Norethindrone


• Norgestimate


• Norgestrel


• Tretinoin

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Bleeding problems (bleeding in the brain) or


• Blood clots, active or history of or


• Head injury or


• Vision problems (problems seeing certain colors)—Should not be used in patients with these conditions.

• Blood vessel problems, history of or


• Hematuria (blood in the urine) caused by or


• Retinal artery or vein occlusion (blood clot in the eye) or


• Seizures, history of or


• Urinary tract problems (e.g., bleeding)—Use with caution. May make these conditions worse.

• Disseminated intravascular coagulation or DIC (blood clotting problem)—Should be treated under strict supervision of an experienced doctor in treating this disorder.

• Kidney disease—Use with caution. The effects may be increased because of slower removal of the medicine from the body.

Proper Use of Cyklokapron

A nurse or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins.

Precautions While Using Cyklokapron

Your doctor will check the progress of you or your child closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it. Blood tests will be needed to check for unwanted effects.

If you or your child will be receiving tranexamic acid injection for longer than several days, your doctor may want you to have your eyes checked regularly by an ophthalmologist (eye doctor). This will allow your doctor to check for unwanted effects that may be caused by this medicine.

Tranexamic acid injection should not be used together with factor IX complex (e.g., BeneFIX®, Proplex® T) or anti-inhibitor coagulant concentrates (e.g., Feiba VH®). Doing so, may increase the chance of having serious side effects.

This medicine may cause some people to become dizzy or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert.

Cyklokapron Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Rare

• Anxiety


• blurred vision


• changes in vision


• chest pain


• confusion


• cough


• dizziness or lightheadedness


• fainting


• fast heartbeat


• greatly increased or decreased frequency of urination or amount of urine


• increased thirst


• loss of appetite


• nausea or vomiting


• numbness of the hands


• pain, redness, or swelling in the arm or leg


• sudden shortness of breath or troubled breathing

Incidence not known

• Convulsions or seizures


• dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position


• sweating


• trouble seeing


• unusual tiredness or weakness

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

• Diarrhea


• mental depression


• muscle twitching or jerking


• nightmares or unusually vivid dreams


• rash


• rhythmic movement of the muscles

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Giddiness


• hives, itching, or redness of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Cyklokapron side effects (in more detail)

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More Cyklokapron resources

• Cyklokapron Side Effects (in more detail)
• Cyklokapron Use in Pregnancy & Breastfeeding
• Cyklokapron Drug Interactions
• Cyklokapron Support Group
• 0 Reviews for Cyklokapron - Add your own review/rating

• Cyklokapron Prescribing Information (FDA)


• Cyklokapron MedFacts Consumer Leaflet (Wolters Kluwer)


• Tranexamic Acid Professional Patient Advice (Wolters Kluwer)


• Lysteda Prescribing Information (FDA)


• Lysteda MedFacts Consumer Leaflet (Wolters Kluwer)


• Lysteda Consumer Overview

Compare Cyklokapron with other medications

• Bleeding Disorder
• Factor IX Deficiency
• Hemophilia A